Lifan's Abstract: Integrating multiple sources of biological data has great potential to provide a better understanding of how genes function together. This study adopted the multiplex framework to integrate different high-throughput data for functional module identification. Our results showed that, with appropriate clustering algorithms, the multiplex formulation achieved a better accuracy for functional module identification.
Yifan's Abstract: Somatic genome alterations (SGAs) are one of the major causes of cancer. Among all the genetic alterations observed in a cancer cell, only a small fraction, known as drivers, directly contribute to tumor growth. The set of drivers in each tumor preserves most of the tumor-specific oncogenic information.
Jenna's Abstract: Resting-state functional magnetic resonance images (rs-fMRI) are invaluable tools for evaluating the neurodevelopmental status of infants and neonates. Unfortunately, rs-fMRI sequences are highly susceptible to motion. Many post-acquisition motion mitigation techniques have been developed to attempt to remove the effects of motion from rs-fMRI sequences.
There has been a lot of hype recently regarding AI and Healthcare. Sanjay will present an introduction to a use-case based approach for AI in Healthcare -- he will cover the broad categories of Financial, Operational and Clinical use-cases with Security as an envelope use-case. The learning objectives are practical business oriented Machine Learning and Deep Learning with specific focus on the data and processes involved.
Imaging genomics is an emerging data science field, where integrative analysis of imaging and omics data is performed to provide new insights into the phenotypic characteristics and genetic mechanisms of normal or disordered biological structures and functions, and to impact the development of new diagnostic, therapeutic and preventative approaches.
Technology to collect and analyse data relating to human health and behaviour will increasingly become a part of everyday life. For the first time, human kind has the opportunity to “time-travel” but not in a mechanical device but through simulation that will allow representations of the past (e.g.
Integration of complex interacting mechanisms is needed to fully understand how toxic environmental contaminants cause human diseases. Proving association of exposure with risk may help formulate polices that identify the exposures or exposure levels to avoid, but they cannot address reducing disease burden in those who were unaware of exposures or when exposures cannot be reduced below safe levels. Mechanistic studies can identify
Sequencing applications such as Whole Genome Seq (WGS), Whole Exome Seq (WES), ChiP Seq, RNA Seq and others are revolutionizing life science research. However, analysis of the Big Data produced from these diverse applications require specialized skills in genomics and create data analysis bottlenecks for most research laboratories.